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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53BP1
All Species:
13.94
Human Site:
S482
Identified Species:
51.11
UniProt:
Q12888
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12888
NP_001135451.1
1972
213574
S482
K
K
D
G
D
M
H
S
S
S
L
T
V
E
C
Chimpanzee
Pan troglodytes
XP_001158270
1972
213535
S482
K
K
D
G
D
L
H
S
S
S
L
T
V
E
C
Rhesus Macaque
Macaca mulatta
XP_001107220
1972
213653
S482
K
K
D
G
D
L
H
S
S
S
L
T
V
E
C
Dog
Lupus familis
XP_849774
1976
214088
S487
K
K
G
G
D
L
H
S
S
S
L
T
V
E
C
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082071
2104
231430
E530
I
N
I
D
L
K
K
E
N
T
T
V
S
K
M
Zebra Danio
Brachydanio rerio
NP_001073639
1709
184731
S282
T
Y
V
Q
E
S
L
S
Q
Q
S
V
D
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798355
2169
238737
I502
V
P
E
P
D
I
E
I
I
D
D
D
Y
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.2
89.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
36.9
34.4
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
100
99.5
98.2
93.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
54.5
51.3
N.A.
N.A.
N.A.
N.A.
37.6
P-Site Identity:
100
93.3
93.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
58
% C
% Asp:
0
0
43
15
72
0
0
0
0
15
15
15
15
0
0
% D
% Glu:
0
0
15
0
15
0
15
15
0
0
0
0
0
72
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% F
% Gly:
0
0
15
58
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
15
0
0
15
0
15
15
0
0
0
0
0
0
% I
% Lys:
58
58
0
0
0
15
15
0
0
0
0
0
0
15
0
% K
% Leu:
0
0
0
0
15
43
15
0
0
0
58
0
0
0
0
% L
% Met:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
15
% M
% Asn:
0
15
0
0
0
0
0
0
15
0
0
0
0
0
0
% N
% Pro:
0
15
0
15
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
15
0
0
0
0
15
15
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
15
0
72
58
58
15
0
15
0
0
% S
% Thr:
15
0
0
0
0
0
0
0
0
15
15
58
0
0
0
% T
% Val:
15
0
15
0
0
0
0
0
0
0
0
29
58
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
0
0
0
0
0
0
0
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _